KMID : 0380020110260010062
|
|
Korean Journal of Biotechnology and Bioengineering 2011 Volume.26 No. 1 p.62 ~ p.68
|
|
The Effect of Lactobacillus plantarum CLP-1 on the Swine Viruses
|
|
Lee Gun-Hee
Kim Young-Hee Cho Hyeon-A Kang Sung-Gi Kim Dong-Gun
|
|
Abstract
|
|
|
To isolate Lactic acid bacteria for animals, we have screened from Kim-chi, swine intestine, swine feces, and dairy products by random selection and anti-viral, antipathogenic bacteria test. Among them, CLP-1 shown that inhibitory effect against rotavirus, porcine epidemic diarrhea (PED) virus, Salmonella sp, and E.coli. By examining biological property, API-ZYM and identified Lactobacillus plantarum by 16S rDNA gene sequence. CLP-1 determined resistance to low pH and bile salt. Futhermore, the cell body of CLP-1 adhered to the intestinal epithelium tissue of swine and Caco-2 cell. CLP-1 was examined on cell immune system modulating activity in vitro. The whole cell and cell culture supernatant was increasing of interferon-¥â activity. And then, CLP-1 increased prevention effect by Salmonella enteritidis infection in SPF chickens. And we determined similar result in pigs.
|
|
KEYWORD
|
|
rotavirus, PED virus, Lactobacillus plantarum, Salmonella
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|